HPLC Column, RP C12, 10um, 4.0mm ID x 50mm Length, 100A. Cogent Brand. 1 EA.

Additional Information:

Cogent RP C12 is a unique reversed-phase HPLC stationary phase based on an adamantane bonded ligand, a rigid diamond-like carbon structure that provides distinctive chromatographic selectivity compared to traditional alkyl phases. The combination of high-purity silica, a narrow particle size distribution, low metal content, complete double endcapping, and the rigid bonded phase design makes this column particularly effective for resolving complex mixtures, fast gradient separations, and applications requiring rapid equilibration between runs. The phase generally provides retention that falls between C8 and C18 columns, making it an excellent choice when C18 retention is excessive and C8 retention is insufficient.

68012-05P-4 is an analytical HPLC column with dimensions of 4.0 mm ID x 50 mm length, packed with 10 µm RP C12 particles featuring a 100 Å pore size. The short column length is well suited for rapid analyses, high-throughput screening, and fast method development workflows. The rigid adamantane bonded phase promotes rapid re-equilibration during gradient methods, while the 10 µm particle size supports higher flow rates and lower operating backpressure. Typical operating flow rates are approximately 0.8–2.0 mL/min depending on mobile phase composition and system configuration.

Compatible with reversed-phase mobile phases, including 100% aqueous conditions, this column maintains reproducible retention without loss of performance between runs. Typical applications include pharmaceutical analysis, environmental testing, quality control, high-throughput screening, method development, and complex mixture separations. This product is supplied as a Special Order Item manufactured specifically upon receipt of order.

Key Benefits

  • Unique adamantane-based RP C12 stationary phase

  • Fully double endcapped chemistry

  • High-purity silica with low metal content

  • Narrow particle size distribution

  • Compatible with 100% aqueous mobile phases

  • Rapid equilibration between runs

  • Excellent for complex mixture separations

  • Retention between C8 and C18 phases

  • 10 µm particles for lower operating backpressure

  • Ideal for high-throughput screening and method development

Typical Applications

  • Analytical HPLC

  • High-throughput screening (HTS)

  • Method development

  • Fast gradient analysis

  • Pharmaceutical analysis

  • Quality control testing

  • Environmental analysis

  • Complex mixture separations

  • Routine laboratory testing

  • Reversed-phase HPLC methods

Specifications

  • Product Type: HPLC Column

  • Stationary Phase: RP C12

  • Chromatography Mode: Reversed Phase

  • Bonded Phase: Adamantane-Based C12 Ligand

  • Endcapping: Fully Double Endcapped

  • Particle Size: 10 µm

  • Pore Size: 100 Å

  • Column Dimensions: 4.0 mm ID x 50 mm

  • Length: 50 mm

  • Typical Flow Rate: 0.8–2.0 mL/min

  • Brand: Cogent

Additional Resources

Special Order Item Information

Important Notes

  • Compatible with 100% aqueous mobile phases

  • Excellent choice when C18 retention is too great and C8 retention is insufficient

  • Rapid re-equilibration supports high-speed gradient methods

  • Frequently selected for complex mixture separations

  • A Cogent Column Filter is included and recommended to help protect the column and extend service life

  • Special Order Item


 

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